ea0027p32 | (1) | BSPED2011
Hawcutt Daniel
, Jorgensen Andrea
, Gardner Christopher
, Peak Matthew
, Couriel Jonathan
, Lacy David
, Newland Paul
, Didi Mohamed
, Pirmohamed Munir
, Smith Rosalind
, Blair Joanne
Background: The activity of the hypothalamicpituitaryadrenal axis (HPA) during inhaled corticosteroid (ICS) treatment of asthma has been studied extensively. To date patient populations have been too small or homogeneous to identify relationships between steroid exposure, patient characteristics and HPA activity. In this abstract we report data from a large, heterogeneous cohort of patients recruited to observational and pharmacogenomic studies.<p class="abstex...